Bioelectronic devices could treat autoimmune disease

Cellulose-Based Bioelectronic Devices

Specific antigen vaccination to treat autoimmune disease.

Specific antigen vaccination by administration of the target antigen in aqueous solution has resulted in significant decreases of disease severity in animal models of experimental allergic encephalomyelitis, type I diabetes, and several forms of antigen-induced arthritis, even if administered after the initiation of symptoms. However, in experimental autoimmune encephalomyelitis (EAE) and type ...

Commentary Inducing autoimmune disease to treat cancer

For many years, visions for development of successful immunotherapy of cancer revolved around the induction of immune responses against tumor-specific ‘‘neoantigens.’’ However, as demonstrated in a recent paper in the Proceedings by Overwijk et al. (1), the generation of tissue-specific autoimmune responses represents an approach to cancer immunotherapy that is gaining momentum. Thus, a new pri...

New Nanobiocomposite Materials for Bioelectronic Devices

We have developed and synthesized nanobiocomposite materials based on graphene, poly(3,4-ethylenedioxythiophene), and glucose oxidase immobilized on the surface of various nanomaterials (gold nanoparticles and multi-walled carbon nanotubes) of different sizes (carbon nanotubes of different diameters). Comparative studies of the possible influence of the nanomaterial's nature on the bioelectroca...

Nabilone could treat chorea and irritability in Huntington's disease.

ory was relatively intact. On discharge, Mr. A continued to show improvement in his cognitive functions, and 2 months after the onset of NMS, his score on MMSE was 25/30 with persistent deficits in immediate and recent memory. He still had retrograde amnesia about the events surrounding the NMS and also had anterograde amnesia with deficits in learning new verbal information. Again, no deficits...